Mechanobiology – When Our Cells Respond to Forces

  • November 13, 2019 • 4:30 PM – 6 PM
  • mySci Resource Center, 6601 Vernon Avenue, St. Louis, MO 63130

Featured Presenter: Amit Pathak, Associate Professor of Mechanical Engineering and Materials Science and Biomedical Engineering, Washington University in St. Louis

FREE and open to all. Middle, high school science, engineering teachers and PLTW teachers encouraged to attend. Registration required.

In disease and development, cells alter their properties, which results in mechanical changes in the body such as stiffening of a tumor, bone loss, inflammation, scarring, or organ deformities. All of these tissue changes vary in their mechanical proper ties. However, it is relatively less known whether the converse is true, i.e., if there are mechanical changes in the tissue, can they alter cellular response? The field of mechanobiology studies how cells respond to varying mechanical properties of their environment, which change from organ to organ and over varying stages or disease and development. This discussion will focus on what is known about mechanobiology and which tools and methods are used in this relatively new field of study.

Dr. Pathak received a Ph.D. in Mechanical Engineering from UC-Santa Barbara after finishing undergraduate studies at the Indian Institute of Technology-Bombay. Prior to joining Washington University in 2013, he completed his postdoctoral fellowship in Bioengineering at UC-Berkeley. He directs Cellular Mechanobiology Laboratory at WashU, which investigates how cells sense and respond to their mechanical environments.

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